科学研究与卫生需求动态关系定量研究———以神经系统疾病为例

doi:10.13266/j.issn.0252-3116.2022.10.005

图书情报工作 ›› 2022, Vol. 66 ›› Issue (10): 59-73.DOI: 10.13266/j.issn.0252-3116.2022.10.005

科学研究与卫生需求动态关系定量研究———以神经系统疾病为例

赵文静^1,2, 张晓含³, 张琳^1,2

1. 武汉大学信息管理学院武汉 430072;
2. 武汉大学科教管理与评价中心武汉 430072;
3. 中国人民大学信息学院北京 100872

收稿日期:2021-08-31 修回日期:2021-12-11 出版日期:2022-05-20 发布日期:2022-06-01
通讯作者: 张琳,教授,博士,博士生导师,通信作者,E-mail:linzhang1117@whu.edu.cn。
作者简介:赵文静,博士研究生;张晓含,硕士研究生。
基金资助:
本文系国家自然科学基金面上项目"科研人员职业生涯的性别差异和影响机理研究:合作、流动与学术表现"(项目编号:71974150)研究成果之一。

A Quantitative Study on the Dynamic Relationship Between Scientific Research and Health Needs:Taking Neurological Diseases as an Example

Zhao Wenjing^1,2, Zhang Xiaohan³, Zhang Lin^1,2

1. School of Information Management, Wuhan University, Wuhan 430072;
2. Center for Science, Technology & Education Assessment(CSTEA), Wuhan University, Wuhan 430072;
3. School of Information, Renmin University of China, Beijing 100872

Received:2021-08-31 Revised:2021-12-11 Online:2022-05-20 Published:2022-06-01

摘要/Abstract

摘要： [目的/意义] 科学技术的进步是保障人类生命安全、提升人类生活福祉的重要手段。定量探究科学研究与卫生需求的动态关系,可为科学研究布局与资源分配提供有益借鉴。[方法/过程] 以全球主要的致残及致死因素之一——神经系统疾病为案例,利用2000-2019年科学文献数据、疾病负担多重指标(伤残调整生命年、致死人数、科研依赖性负担)与人类发展指数,在构建科学研究与卫生需求关系定量分析框架的基础上,探析神经系统疾病负担与科研产出的匹配性、相关性及回归关系。[结果/结论] 研究发现,过去20年间,神经系统疾病的负担及文献产出在全球范围内均呈现上升趋势。整体而言,科学界对此类疾病给予了较为充足的关注,但其中部分疾病(如偏头痛)的研究力度相对欠缺。不同发展水平国家视角下,神经系统疾病负担主要集中于超高水平国家,此类国家也是应对该疾病负担的核心科研力量。细分至具体疾病来看,超高水平国家对于中低水平国家负担相对较高的疾病(如癫痫)的科研关注度较弱。回归分析结果表明,疾病负担与文献产出显著正相关,说明疾病负担的增长对该疾病相关文献产出有正向影响。相较于伤残调整生命年,更为直观的致死人数对科学文献产出的影响更大。此外,本研究论证创新性指标"科研依赖性负担"的现有局限性,并基于数据结果提出相关建议。

关键词: 科学研究, 卫生需求, 疾病负担, 伤残调整生命年, 神经系统疾病

Abstract: [Purpose/Significance] The advancement of science and technology plays a vital role in safeguarding human life security and enhancing human well-being. Quantitative research on the dynamic relationship between scientific research and health needs could provide beneficial references for layout and resource allocation of scientific research.[Method/Process] On the basis of construction of a quantitative analysis framework of the relationship between scientific research and health needs, this paper took one of the world's major disability and mortality causes, namely neurological diseases, as a case study and used scientific academic publications, multiple indicators of disease burden (disability-adjusted life years, number of fatalities, research-dependent fraction of global burden of disease) and the Human Development Index (HDI) from 2000 to 2019 to explore the matching, correlation, and regression relationships between the burden of neurological diseases and scientific research outputs.[Result/Conclusion] The results show that the burden of neurological diseases and academic outputs have been increasing globally from 2000 to 2019. In general, the scientific community has given more than adequate attention to such diseases, but some of them (e.g., migraine) have been relatively poorly studied. From the perspective of countries at different HDI levels, the burden of neurological diseases is mainly concentrated in very-high level countries, and such countries are also the main contributors of relevant research. In terms of specific diseases, very-high level countries have paid less scientific attention on diseases (e.g., epilepsy) with relatively high burden in low- and medium-level countries. The regression analysis show that increase of disease burden had a positive impact on academic outputs. Further, the number of academic outputs is affected greater by the number of deaths in comparison to the disability-adjusted life years. In addition, the existing limitations of an innovative indicator "research-dependent fraction of global burden of disease" are also demonstrated by this paper, and some related suggestions are put forward based on the data results.

Key words: scientific research, health needs, disease burden, disability-adjusted life years, neurological diseases

中图分类号:

G250
R195.4

赵文静, 张晓含, 张琳. 科学研究与卫生需求动态关系定量研究———以神经系统疾病为例[J]. 图书情报工作, 2022, 66(10): 59-73.

Zhao Wenjing, Zhang Xiaohan, Zhang Lin. A Quantitative Study on the Dynamic Relationship Between Scientific Research and Health Needs:Taking Neurological Diseases as an Example[J]. Library and Information Service, 2022, 66(10): 59-73.

参考文献

[1] 2019年度国家自然科学基金改革举措[EB/OL].[2021-12-05].http://www.nsfc.gov.cn/nsfc/cen/xmzn/2019xmzn/ggjc.html.
[2] 马来平.科学的社会性、自主性及二者的契合[J].哲学分析,2011, 2(6):133-146,194.
[3] HESSELS L K, VAN LENTE H, SMITS R.In search of relevance:the changing contract between science and society[J].Science and public policy,2009, 36(5):387-401.
[4] 李瑞青. 大卫·古斯顿的科学社会契约理论研究[D]. 南宁:广西大学,2017.
[5] CIARLI T, RAFOLS I.The relation between research priorities and societal demands:the case of rice[J].Research policy,2019, 48(4):949-967.
[6] WALLACE M L, RàFOLS I.Institutional shaping of research priorities:a case study on avian influenza[J].Research policy,2018, 47(10):1975-1989.
[7] CASSI L, LAHATTE A, RAFOLS I, et al.Improving fitness:mapping research priorities against societal needs on obesity[J].Journal of informetrics,2017, 11(4):1095-1113.
[8] HSIEHCHEN D, ESPINOZA M, HSIEH A.Disease burden and the advancement of biomedical knowledge[J].Scientometrics,2016, 110(1):321-333.
[9] GILLUM L A, GOUVEIA C, DORSEY E R, et al.NIH disease funding levels and burden of disease.[J].PLoS ONE,2011, 6(2):e16837.
[10] OVERLAND I, K. S B.The misallocation of climate research funding[J].Energy research & social science,2020, 62:101349.
[11] BEGUM M, LEWISON G, JASSEM J, et al.Mapping cancer research across Central and Eastern Europe, the Russian Federation and Central Asia:implications for future national cancer control planning[J].European journal of cancer,2018, 104:127-136.
[12] EVANS J A, SHIM J M, IOANNIDIS J P.Attention to local health burden and the global disparity of health research[J].PLoS ONE,2014, 9(4):e90147.
[13] RØTTINGEN J-A, REGMI S, EIDE M, et al.Mapping of available health research and development data:what's there, what's missing, and what role is there for a global observatory?[J].Lancet,2013, 382(9900):1286-1307.
[14] ATAL I, TRINQUART L, RAVAUD P, et al.A mapping of 115 000 randomized trials revealed a mismatch between research effort and health needs in non-high-income regions[J].Journal of clinical epidemiology,2018, 98:123-132.
[15] ZHANG L, ZHAO W, LIU J, et al.Do national funding organizations properly address the diseases with the highest burden?:observations from China and the UK[J].Scientometrics,2020, 125(2):1733-1761.
[16] KINGE J M, ROXRUD I, VOLLSET S E, et al.Are the Norwegian health research investments in line with the disease burden?[J].Health research policy and systems,2014, 12(64):1-98.
[17] CONFRARIA H, WANG L.Medical research versus disease burden in Africa[J].Research policy,2020, 49(3):103916
[18] KALITA A, SHINDE S, PATEL V.Public health research in India in the new millennium:a bibliometric analysis[J].Global health action,2015, 8(1):27576.
[19] FOROUGHI Z, SIAMIAN H, ALIZADEH-NAVAEI R, et al.The relation between Iranian Medical Science Research in PubMed and Burden of Disease[J]. Acta informatica medica, 2016, 24(4):271-276.
[20] BEGUM M, LEWISON G, WRIGHT J S, et al.European non-communicable respiratory disease research, 2002-13:bibliometric study of outputs and funding[J].PLoS ONE,2016, 11(4):e0154197.
[21] CUSCHIERI S, PALLARI E, TERZIC N, et al.Mapping the burden of diabetes in five small countries in Europe and setting the agenda for health policy and strategic action[J].Health research policy and systems,2021, 19(43):1-10.
[22] FONSECA B D P, ALBUQUERQUE P C, ZICKER F.Neglected tropical diseases in Brazil:lack of correlation between disease burden, research funding and output[J].Tropical medicine & international health,2020, 25(11):1373-1384.
[23] LI A, LEWISON G.Chinese Cancer Research in 2009-18 and the Disease Burden[J].Cancer management and research,2020, 12:5031-5040.
[24] YEGROS-YEGROS A, VAN DE KLIPPE W, ABAD-GARCIA M F, et al.Exploring why global health needs are unmet by research efforts:the potential influences of geography, industry and publication incentives[J].Health research policy and systems,2020, 18(1):1-14.
[25] WHO. Neurological disorders-public health challenges[EB/OL].[2021-04-17].https://www.who.int/mental_health/neurology/introduction_neuro_disorders_public_h_challenges.pdf?ua=1.
[26] WHO.The top 10 causes of death[EB/OL].[2021-05-15].https://www.who.int/en/news-room/fact-sheets/detail/the-top-10-causes-of-death.
[27] WHO. Disease, injury and causes of death country,regional and global estimates, 2000-2015[EB/OL].[2021-12-04]. https://www.who.int/healthinfo/global_burden_disease/estimates_country_2000_2015/en/.
[28] 龚旭辉, 冯广, 周瀚章, 等.2014-2018年癫痫脑电研究文献计量分析[J].工业控制计算机,2019, 32(2):114-115.
[29] 王君兰, 王艳梅.基于文献计量的阿尔茨海默病研究态势分析[J].世界科技研究与发展,2018, 40 (5):465-476.
[30] 张兵, 张红梅, 姜洋, 等.多发性硬化症及其治疗药物研发的文献计量分析[J].中华医学图书情报杂志,2013, 22(9):47-49.
[31] The royal college of physicians and surgeons of Canada. Defining societal health needs[R]. Ottawa:The Royal College,2012.
[32] WHO. Measles-Key facts[EB/OL].[2021-12-01]. https://www.who.int/news-room/fact-sheets/detail/measles.
[33] HAGENAARS N, DE KRUIF T, VAN DE LAAR L, et al.The relationship between publication volume of biomedical research and burden of disease[EB/OL].[2022-02-13].https://osf.io/jeuar/.
[34] LEWSION G. Have the European Union programmes made a difference to biomedical research outputs?[C]//18th International conference on scientometrics and informetrics. KU Leuven:Belgium, 2021:651-661.
[35] 严青利, 张勇.医学主题词表(MeSH)评述[J].情报杂志,2001(8):64-66.
[36] The World Bank. World development report, 1993[R]//Investing in health.New York:Oxford University Press for the World Bank,1993.
[37] 世界卫生组织-全球疾病负担[EB/OL].[2021-05-14] https://www.who.int/topics/global_burden_of_disease/zh/.
[38] UNDP. The 2020 Human Development Report-The next frontier:human development and the anthropocene[R/OL].[2021-11-16] http://hdr.undp.org/sites/default/files/hdr2020.pdf.
[39] FEIGIN V L, ABAJOBIR A A, ABATE K H, et al.Global, regional, and national burden of neurological disorders during 1990-2015:a systematic analysis for the global burden of disease study 2015[J].The Lancet neurology,2017, 16(11):877-897.
[40] MULA M, KAUFMAN K R.Double stigma in mental health:epilepsy and mental illness[J].BJPsych open,2020, 61(4):1-5.
[41] O'BRIEN R M.A caution regarding rules of thumb for variance inflation factors[J].Quality & quantity,2007, 41(5):673-690.
[42] TERRY R F, SALM J F, NANNEI C, et al.Creating a global observatory for health R&D[J].Science,2014, 345(6202):1302e4.
[43] Institute of Medicine (US) Committee on the NIH Research Priority-Setting Process. Scientific opportunities and public needs:improving priority setting and public input at the National Institutes of Health.[M].Washington, DC:National Academies Press,1998.

科学研究与卫生需求动态关系定量研究———以神经系统疾病为例

A Quantitative Study on the Dynamic Relationship Between Scientific Research and Health Needs:Taking Neurological Diseases as an Example

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