[Purpose/significance] Based on the innovation ecosystem scenario, this paper explores the knowledge integration of enterprises, and provides a new perspective for improving the knowledge integration effect and innovative ability of enterprises.[Method/process] Through the theoretical review of the innovation ecosystem and knowledge integration, this paper studied the process and dynamic of knowledge integration around two essential characteristics of "innovative" and "ecological", and proposed safeguard measures.[Result/conclusion] In the context of innovation ecosystem, knowledge integration of enterprises has undergone two stages:external knowledge intake and internal knowledge assimilation, and the effective integration of knowledge can be realized under the synergy of enterprises' innovative source power, industry-university-research cooperation motivation and innovative environment drive force. Furthermore, safeguard measures can be proposed for the effectiveness of knowledge integration from the three levels of innovation environment, universities and research institutes, enterprises.
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