[Purpose/Significance] This paper studies the impact of venture capital on the transformation of scientific and technological achievements of hard science and technology enterprises and verifies the scientific and technological investment method of "early, small and new investment" through empirical data to guide and optimize technology transfer and scientific and technological investment.[Method/Process] Based on 202 investment data of well-known hard science and technology investment institutions, the analytical framework of investment decision-making was constructed. This paper studied the impact of venture capital on hard science and technology enterprises from the perspectives of enterprise growth and the rotation of venture capital.[Result/Conclusion] Data analysis shows that venture capital has a significant role in promoting the growth of hard science and technology enterprises. Projects with earlier investment rounds have higher growth and fund returns. The scientific and technological content of the project and the difficulty of investment decision-making are increasing. Venture capital institutions should strengthen the project exploration and screening advantages and improve the level of investment decision-making.
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