指出跨学科与转化研究模式的兴起为图书情报学领域提供了新的挑战与机遇,并分析国外图书馆或情报学机构支持转化研究的实践或行动,包括:①转化型研究文献的检索;②临床数据管理;③生物信息学工具与方法支持;④研究合作支持;⑤转化研究的追踪与评估。在此基础上提出国内图书情报服务支持医学转化研究的优先努力方向:①应用文献分析方法测度和揭示转化研究进程;②帮助科研人员寻找最佳的合作研究者;③建立科学家的科研合作信息平台;④设计适合国内转化研究的绩效评估体系。
The interdisciplinary and translational research model brings new challenges and opportunities for the development of library and information science. Efforts of library and informatics' support services for translational research include translational research literatures retrieval, clinical information management, bioinformatics tools and methods support, research collaboration support, and tracing and evaluating services. Universities, hospitals and scientific research institutes in China are developing translational medical research centers. To solve the problems in the translation, both library and information services should make four priority efforts combined with their own advantages. Firstly, they should measure and reveal the process of translational research in special areas through literature analysis. Secondly, they should help scientists to discover and find best cooperators with intelligence analysis and mining method. Thirdly, they should establish a collaborative information platform for scientists and researchers, to know about outputs each other and find cooperators and cooperative directions. Finally, it is necessary to develop performance evaluation index system suitable for Chinese translational research work.
[1] Zerhouni E. Medicine: The NIH roadmap[J]. Science, 2003,302(5642):63-72.
[2] Sung N S, Crowley W F Jr, Genel M, et al. Central challenges facing the national clinical research enterprise[J].Journal of the American Medical Association,2003, 289(10):1278-1287.
[3] 沈晓明. 应重视医学研究向卫生政策的转化研究[J].中华医学杂志,2011,91(24):1657-1658.
[4] Hunt J D.Use of social network analysis tools to validate a resources infrastructure for interinstitutional translational research:A case study[J]. Journal of the Medical Library Association,2012, 100(1): 48-54.
[5] 王肖,徐腾达,尹文,等.推动转化医学的发展是急诊临床科学决策的关键[J].中华急诊医学杂志,2012,21(6):568-571.
[6] National Center for Advancing Translational Sciences (NCATS)[EB/OL].[2013-07-27].http://www.ncats.nih.gov/about/about.html.
[7] Balas E A, Boren S A. Managing clinical knowledge for health care improvement[M].Stuttgart:Schattauer Verlagsgesellschaft mbH, 2000:65-70.
[8] AAAS/Science panel discussion "Library-based support for translational medicine" at Medical Library Association 2011[EB/OL].[2013-06-24]. http://www.sciencemag.org/site/help/librarians/.
[9] From bench to bedside: Librarian's roles in translational medicine[EB/OL].[2013-06-25]. http://npc.mlanet.org/mla11/?p=1365.
[10] Clinical and translational science research: Library support 2012[EB/OL].[2013-06-24]. http://nnlm.gov/mar/blog/2012/03/30/clinical-and-translational-science-research-library-support-2012/.
[11] Fontelo P, Liu F. Finding translational science publications in MEDLINE/PubMed with translational science filters[J].Clinical and Translational Science, 2011,4(6):455-459.
[12] American Medical Informatics Association(AMIA). Clinical research informatics webpage[EB/OL].[2013-10-20].http://www.amia.org/applications-informatics/clinical-research-informatics.
[13] Snyder D C, Epps S, Beresford H F, et al. Research management team(RMT): A model for research support-services at Duke University[J].Clinical and Translational Science, 2012,5(6):464-469.
[14] 张大保,张敏.生物信息学与转化医学研究[J].转化医学研究(电子版),2012,2(4):41-52.
[15] 张士靖,秦方,姚强,等.国内外转化医学研究机构的特色分析[J].华中科技大学学报(医学版),2012,41(3):324-328.
[16] Contopoulos-ioannidis D G, Ntzani E, Ioannidis J P. Translation of highly promising basic science research into clinical applications[J].American Journal of Medicine,2003,114(6):477-484.
[17] Cathy C. Sarli, MLS, AHIP. Beyond citation analysis:A model for assessment of research impact[J].Journal of the Medical Library Association, 2010,98(1):17-23.
[18] Sarli C C, Holmes K L. Update to "Beyond citation analysis: A model for assessment of research impact"[J].Journal of the Medical Library Association, 2012,100(2):82.
[19] Tracking & evaluation [EB/OL].[2013-07-12]. http://icts.wustl.edu/icts-researchers/about/icts-administration/tracking-and-evaluation.
[20] Sarkar I N. Biomedical informatics and translational medicine[J].Journal of Translational Medicine,2010(8):22.
[21] 我国临床和转化医学喜忧参半[EB/OL].[2013-07-27]. http://www.bioexpress.ac.cn/zhutis.asp?id=14395.
[22] Lewison G, Paraje G. The classification of biomedical journals by research level[J]. Scientometrics,2004, 60(2):145-157.
[23] Cambrosio A, Keating P, Mercier S, et al. Mapping the emergence and development of translational cancer research[J].European Journal of Cancer, 2006, 42(18):3140-3148.
[24] Jones D S,Cambrosio A, Mogoutov A. Detection and characterization of translational research in cancer and cardiovascular medicine[J].Journal of Translational Medicine,2011(9):57.
[25] Weber G M. Identifying translational science within the triangle of biomedicine[J].Journal of Translational Medicine, 2013(11):126.
[26] 杜建,唐小利,张燕舞,等. 引文网络加速转化医学T1-T2-T3阶段的转化进程[J]. 中华临床营养杂志,2013,21(2):98-102.
[27] Sharma A. A measure of respect for translational research[J]. Science,2007,318(5849):391-393.
[28] Butler D. Translational research:Crossing the valley of death[J]. Nature,2008, 453(7197):840-842.
[29] 钟世镇. 请关注转化医学理念[J]. 科技导报,2012,30(27):3.
