[Purpose/significance] To discuss the relationship between health risk perception and information interaction behavior is of great significance to accurately grasp the information needs and supply methods in the context of health risk perception, and then to improve the level of public risk perception. [Method/process] The existing theories of risk information seeking were systematically reviewed to theoretically explore the relevant factors and their relationships of information interaction behavior in the context of health risk perception. Then the model of the relationship between health risk perception and information behavior was constructed, the corresponding research variables were proposed. [Result/conclusion] Users’ health risk information interaction behavior is affected by users’ individual characteristics, health risk perception, affection, information adequacy, perceived information gathering capacity and the characteristics of information. The model constructed from these related factors of health risk perception and information interaction behavior reveals the dynamic interaction and iteration process between users and information systems from the surface, cognitive and contextual levels.
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