[Purpose/significance] This paper proposes the intelligence empirical research and service strategies of university libraries, which could promote the popularization and expansion of services, and provide a service paradigm and methodological path reference for university libraries to carry out similar services. [Method/process] In this paper, the empirical research method, inductive method and literature research method were used. In the process of discipline construction, the three application scenarios of "team building", "innovation guidance" and "performance improvement" were the core, and three service modules were proposed to match them: helping the construction of first-class teaching staff, scientific research innovation inspiration and cutting-edge direction guidance, and academic output and influence monitoring, each service includes 3 service categories, and a series of characteristic empirical research methods were used as supporting contents for each category. Ultimately, they constituted a "nine-box" distributed intelligence research and service strategy. [Result/conclusion] Based on the intelligence empirical research and service strategies based on first-class discipline construction application scenarios, the system could deeply integrate the research methods with the application scenarios, and establish a correlation channel between the intelligence theory and the service practice, which could enrich the intelligence research methodology, and could improve the accuracy of methodology’s guiding for the service practice. Remarkable achievements have been made in the process of helping the construction of first-class disciplines