[Purpose/Significance] Reconstructing the collaborative governance framework of national digital academic resources information security in the cloud computing environment in combination with the information ecology theory and modern governance theory is to effectively govern the information security. [Method/Process] Based on the analysis of the relationship between information ecology and information security collaborative governance of national digital academic resources, this paper constructed the collaborative governance framework of national digital academic resources information security from the perspective of information ecology and analyzed the relationship between its constituent elements. At the same time, this paper analyzed the information security collaborative governance object, governance subject, governance environment and collaborative governance mechanism within each element of national digital academic resources in the computing cloud from the perspective of information ecology. [Result/Conclusion] This paper clarifies the subjects and objects of governance in the information ecosystem for the information security collaborative governance of national digital academic resources in the cloud computing environment. It aims to provide a reference for realizing the collaborative governance of national digital academic resources information security in the cloud computing environment.