[Purpose/Significance] Under the development trend and policy background of two-wheel drive in basic research, the research on measurement method for translation of basic biomedical research can provide clues for identification of academic papers with translational potential, and provide tools for the translational effect evaluation of basic research. [Method/Process] Combined with performance of the basic research transformation process in the field of biomedicine in the dimensions of research contents and research institutions, this paper constructed two basic-applied concept quantification model; then, identified words representing basic-applied concept by word list matching method, and calculated the measurement variables of application level of papers; finally, made use of the measurement variables above to classify the research levels of papers by constructing quantitative Pasteur’s quadrant model, and designed indicators to measure the translational degree of basic research to downstream applied research based on basic-applied research level changes in citation relationships. [Result/Conclusion] For empirical analysis, the paper selects dataset from papers produced by stem cell and immunology general projects funded by National Natural Science Foundation of China (approved in 2010 and 2011). The feasibility and effectiveness of the method proposed in this study are verified. Among the 5 conversion indicators designed, TS_PERC, TS_HOSP and TS_COM can indicate the papers’ potential of clinical translation or technical translation. They can assist in early identification of translational potential of basic research findings, shortterm evaluation of the translational effect of basic research in biomedicine and other scenarios.
Tao Siyu
,
Tan Zongying
. Research on Measurement Method for Translation of Basic Biomedical Research: Taking the Papers from General Projects Funded by the National Natural Science Foundation of China in the field of Stem Cell and Immunology as Examples[J]. Library and Information Service, 2023
, 67(14)
: 50
-61
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DOI: 10.13266/j.issn.0252-3116.2023.14.006
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